Using the MANTIS Liquid Dispenser to Generate Joint Whole-Genome and mRNA Libraries in Single Cells With DNTR-seq

Using the MANTIS^® Liquid Dispenser to Generate Joint Whole-Genome and mRNA Libraries in Single Cells With DNTR-seq

Direct Nuclear Tagmentation and RNA sequencing (DNTR-seq) is a method to jointly sequence genomic DNA and mRNA from the same single cell to determine the direct effect of genotype on phenotype. This application note illustrates how the MANTIS^® liquid dispenser enables multiplex analysis of both DNA and RNA libraries for 1500 cells in a day.

The MANTIS^® Liquid Dispenser

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