Application Notes

Refine Your Search

Generating High-Quality cDNA Libraries for Efficient Sequencing of T-cell Receptor mRNA from Single Cells

Application Note

Single-cell omics offer precise insights into individual cells, including gene expression and variable protein sequences. rhTCRseq enables efficient TCR analysis at single-cell level, supported by MANTIS Liquid Dispenser for quality cDNA libraries.

Learn More

Fast Lab-Scale Protein Refolding by Filter Dialysis on the µPULSE TFF System

Application Note

The µPULSE, a lab-scale TFF system, offers customizable pressures for protein refolding, yielding faster and higher specific activity results compared to equilibrium dialysis. This applies broadly to buffer exchange scenarios.

Learn More

Automation of Single Cell Plating Utilizing the TEMPEST® Dispenser

Application Note

This study compares the dispensing and analysis of CHO-K1 cells to a 384-well plate using the automated FORMULATRIX TEMPEST® Liquid Dispenser versus an electric hand pipette.

Learn More

Semi-Automated, Non-contact, and Tip-Free Magnetic Bead-based DNA Purification

Application Note

We describe an improved semi-automated workflow using MANTIS in combination with BlueWasher for the purification of nucleic acids that addresses the shortcomings of conventional pipetting.

Learn More

Fully Automated, Non-contact, and Tip-Free Magnetic Bead-based DNA Purification

Application Note

Magnetic beads can vary in surface coatings and chemistries for magnetic-based cleanup of DNA, RNA, and proteins with minimal processing. Our presented solution combines micro diaphragm pump technology with centrifugal plate washing to supercharge magbead-based workflows.

Learn More

Influence of Humidity on Drop Evaporation

Application Note

In this application note, we assess the effects of humidity on the droplet size and composition during the course of crystallization plate preparation.

Learn More

Easily Track Your Crystals with Synchrotron Trip Management

Application Note

This application note explains how the Synchrotron Trip Management feature in ROCK MAKER helps you stay on track by keeping all of your trip data in one place. From picking which pucks and dewars you want to use, to virtually harvesting your crystals before you harvest the real ones, to storing all of your trip data in an easy-to-use report.

Learn More

Effortlessly Add Multiple Fragments for Co-crystallization Experiments using the ROCK MAKER – Crystallization Software

Application Note

ROCK MAKER expanded its capabilities to allow for the easy creation of co-crystallization experiments using fragments and ligands.

Learn More

Using the MANTIS Liquid Dispenser to Generate Joint Whole-Genome and mRNA Libraries in Single Cells With DNTR-seq

Application Note

Direct Nuclear Tagmentation and RNA sequencing (DNTR-seq) jointly sequences genomic DNA and mRNA from the same single cell to determine the direct effect of genotype on phenotype. This application note illustrates how the MANTIS liquid dispenser enables multiplex analysis of both DNA and RNA libraries for 1500 cells in a day.

Learn More

Iterative Screen Optimization (ISO) of Macromolecular Crystals

Webinar | Application Note

The ROCK MAKER® Crystallization Software can automatically generate experiments for each ISO step, adjusting the precipitant concentration of each condition based on user scores.

Learn More