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Fast Formulation of a Purified Recombinant L-asparaginase Using µPulse – TFF System

Application Note

The µPulse filter chips can be cleaned in place and reused several times with negligible difference in filtration rates. We conclude that the use of the µPulse TFF system is a fast, scalable, and cost-effective approach for formulation of the purified recombinant proteins, and other biomolecules.

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Accelerating Research with Organoid Disease Models Using Automated Imaging and Dispensing

Article

Effective automated dispensing using the Mantis (Formulatrix) in combination with live-cell image analysis on the IncuCyte SX5 (Sartorius) opens up the possibility of running high-scale organoid applications such as small molecule screens, quantitative quality assurance processes, and high-volume expansion experiments.

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Generating High-Quality cDNA Libraries for Efficient Sequencing of T-cell Receptor mRNA from Single Cells

Application Note

Single-cell omics offer precise insights into individual cells, including gene expression and variable protein sequences. rhTCRseq enables efficient TCR analysis at single-cell level, supported by MANTIS Liquid Dispenser for quality cDNA libraries.

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Fast Lab-Scale Protein Refolding by Filter Dialysis on the µPULSE TFF System

Application Note

The µPULSE, a lab-scale TFF system, offers customizable pressures for protein refolding, yielding faster and higher specific activity results compared to equilibrium dialysis. This applies broadly to buffer exchange scenarios.

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Automation of Single Cell Plating Utilizing the TEMPEST® Dispenser

Application Note

This study compares the dispensing and analysis of CHO-K1 cells to a 384-well plate using the automated FORMULATRIX TEMPEST® Liquid Dispenser versus an electric hand pipette.

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Semi-Automated, Non-contact, and Tip-Free Magnetic Bead-based DNA Purification

Application Note

We describe an improved semi-automated workflow using MANTIS in combination with BlueWasher for the purification of nucleic acids that addresses the shortcomings of conventional pipetting.

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Fully Automated, Non-contact, and Tip-Free Magnetic Bead-based DNA Purification

Application Note

Magnetic beads can vary in surface coatings and chemistries for magnetic-based cleanup of DNA, RNA, and proteins with minimal processing. Our presented solution combines micro diaphragm pump technology with centrifugal plate washing to supercharge magbead-based workflows.

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Influence of Humidity on Drop Evaporation

Application Note

In this application note, we assess the effects of humidity on the droplet size and composition during the course of crystallization plate preparation.

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Easily Track Your Crystals with Synchrotron Trip Management

Application Note

This application note explains how the Synchrotron Trip Management feature in ROCK MAKER helps you stay on track by keeping all of your trip data in one place. From picking which pucks and dewars you want to use, to virtually harvesting your crystals before you harvest the real ones, to storing all of your trip data in an easy-to-use report.

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Effortlessly Add Multiple Fragments for Co-crystallization Experiments using the ROCK MAKER – Crystallization Software

Application Note

ROCK MAKER expanded its capabilities to allow for the easy creation of co-crystallization experiments using fragments and ligands.

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