Cellmatic Cold Dispense
Automated Cold Reagent Storage
Designed for automated reagent preparation and delivery within temperature-controlled, integrated laboratory workflows.
1 mL/s
Dispense Rate
4 %
CV at 2 mL Dispense
0.1 mL
Dispensing Accuracy
ISO 5
Cleanroom Class - Dispensing Channel
On-Demand Reagent Preparation Within a Controlled
Cold Environment
On-Demand Reagent Preparation Within a Controlled Cold Environment
The Cellmatic Cold Dispense stores up to five reagent containers, either 1 L bottles or 5 L media bags, and automatically dispenses them into SBS-format reservoirs based on user-defined protocols. Reagent containers, plumbing lines, and the dispensing station are all housed within the refrigerated chamber, preserving reagent stability from storage through to delivery. Reservoirs are automatically delidded for dispensing and relidded before handoff, minimizing contamination risk and evaporation at every step.
Right Reagent, Right Time
Reagents dispensed on demand, eliminating manual loading and preventing warming on deck
Automated Reservoir Preparation
Multiple bulk reagents can be dispensed into a single reservoir, simplifying preparation for complex protocols
Maintain Sterility at All Times
The dispensing area is positively pressurized with HEPA filtration and meets ISO 5 cleanroom standards
Key Features
Software-Defined Reagent Protocols: Reagent compositions and volumes are defined entirely in the software, and the system dispenses automatically, eliminating manual premixing and enabling multiple users and protocols to run simultaneously.
Bulk Reagent Storage: Stores up to five reagent containers (1 L bottles or 5 L media bags) within the refrigerated chamber. Reagents, plumbing lines, and the dispense station all remain at a controlled cold temperature throughout.
Automated Delidding and Relidding: Reservoirs are automatically delidded inside the dispensing station, filled according to protocol, and relidded before exiting the system, reducing evaporation and protecting reagents from contamination.
On-Board Reagent Mixing: Multiple reagents can be combined into a single reservoir within the system, enabling the automated preparation of custom reagent mixtures without manual intervention.
ISO 5-Compliant Dispensing Chamber: The dispensing area is positively pressurized with HEPA filtration and meets ISO 5 cleanroom standards, with UV sterilization and internal HEPA air filtration to maintain a clean dispensing environment.
Built-In CCTV Monitoring: An integrated camera inside the chamber enables remote monitoring of dispensing operations and system status without physical access.
Precise Temperature Control: A variable-speed compressor with automatic defrost, soft-start control, and real-time pressure and temperature monitoring delivers ±0.2 °C temperature accuracy at a 4 °C setpoint.
Ethernet and API Integration: Supports remote access, scheduling, and control by third-party automation platforms via Ethernet connectivity and an available software API.
Automating Reagent Preparation From Storage to Handoff
Rather than delivering reagents directly to a single instrument, the Cellmatic Cold Dispense prepares filled reservoirs that a robotic arm retrieves and transfers to any liquid handler in the workcell. This makes a single prepared reservoir available across the full system rather than tethering reagent delivery to a single instrument. Users define reagent compositions and dispensing schedules in software; the system handles the rest, including multi-reagent mixing into a single reservoir when the protocol requires it. The result is a hands-off preparation step that supports flexible experiment design and minimizes waste by dispensing only what is needed for each run.
Clean, Stable, and Built for Continuous Operation
The dispensing chamber is positively pressurized and conforms to ISO 5 cleanroom standards, with HEPA air filtration and UV sterilization maintaining a contamination-free environment throughout reagent preparation. Automated delidding and relidding of reservoirs further limit exposure of reagents to the ambient environment. A variable-speed compressor maintains ±0.2 °C accuracy at a 4 °C setpoint, with automatic defrost cycles, soft-start control, and real-time monitoring of suction and discharge line pressure and temperature. The modular design simplifies maintenance and minimizes downtime in automation environments requiring continuous operation.
Part of the Cellmatic Cell Culture Automation Platform
The Cellmatic Cold Dispense integrates natively with the Cellmatic Cold Store, Incubator, and automated plate washer, purpose-built modules that together cover the full cell culture workflow. Each component is also compatible with third-party robotic platforms, giving labs the flexibility to adopt Cellmatic components selectively within existing or custom workcell designs.
