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51 entries « 1 of 3 »

Wright, Gerard

A microbial natural product fractionation library screen with HRMS/MS dereplication identifies new lipopeptaibiotics against Candida auris Journal Article

In: 2025.

Abstract | Links | Tags: TEMPEST

Bildziukevich, Uladzimir

Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Kovar, Peter

Development of a sensitive high-throughput enzymatic assay capable of measuring sub-nanomolar inhibitors of SARS-CoV2 Mpro Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Dufresne, Karine

Discovery of an antivirulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin-1 production Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

DeRatt, Lindsey G.

Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Lamond, Angus Iain

Cell analysis Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Dufresne, Karine

Discovery of an anti-virulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin 1 (TSST-1) production Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

DeRatt, Lindsey G.

Discovery of Alternative Binding Poses through Fragment-Based Identification of DHODH Inhibitors Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Sedlak, David

Unique and Common Agonists Activate the Insect Juvenile Hormone Receptor and the Human AHR Journal Article

In: 2024.

Abstract | Links | Tags: TEMPEST

Li, Keyu

Overcome the challenge for intratumoral injection of STING agonist for pancreatic cancer by systemic administration Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Cook, Michael A

Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Bordeleau, Emily

Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Kamuntavicius, Gintautas

Accelerated Hit Identification with Target Evaluation, Deep Learning and Automated Labs: Prospective Validation in IRAK1 Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Johnston, Zoe C

Sperm Cell Painting: A Mechanism Driven Approach for Drug Discovery in Human Spermatozoa Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Vasta, James D.

Protomer selectivity of type II RAF inhibitors within the RAS/RAF complex Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Bouguenina, Habib

A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Platani, Melpomeni

Screening for variable drug responses using human iPSC cohorts Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Bouguenina, Habib

iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Dama, Adam C.

BacterAI maps microbial metabolism without prior knowledge Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

Albors, Aida Rodrigo, et al.

An ependymal cell census identifies heterogeneous and ongoing cell maturation in the adult mouse spinal cord that changes dynamically on injury Journal Article

In: 2023.

Abstract | Links | Tags: TEMPEST

51 entries « 1 of 3 »