Beyond Spin Columns: Automate Your IVT-mRNA Processing for Higher Yields and Faster Results with the µPulse® - TFF System

About

 

In vitro transcribed (IVT) mRNA production is central to vaccine development, therapeutic design, and molecular biology research. Buffer exchange is required at multiple points in the IVT mRNA workflow to remove reaction components that can interfere with subsequent steps or affect RNA stability.

 

Conventional silica-based spin columns, though widely used, are slow, labor-intensive, and difficult to scale, often causing sample loss and inconsistent recovery.

This webinar will demonstrate how the µPulse - TFF system automates this critical process, transforming it into a fast and walk-away operation. Completing both post-IVT and post-capping buffer exchanges in just 1–1.5 hours with minimal manual intervention compared to over 2 hours and 10–12 manual steps with spin columns, the µPulse delivers substantial time savings while maintaining high RNA recovery, integrity, and consistency at both 1 mg and 5 mg synthesis scales.

 

Join us to discover how the µPulse simplifies IVT mRNA processing by reducing manual intervention and processing time while maintaining high yield and RNA quality to deliver reproducible, scalable workflows.

When


December 11th 2025

Session 1

10:00 AM - 10:30 AM CET

(09:00 AM - 09:30 AM GMT)

Session 2

01:00 PM - 01:30 PM ET

(10:00 AM - 10:30 AM PT)

Muhammad Sajed Application Scientist at Formulatrix

About the Speaker:

Muhammad Sajed, PhD, is currently working at Formulatrix as an application scientist for the µPulse-TFF system and its applications in biological research. His areas of expertise include the production and purification of therapeutic enzymes, cell culturing, and industrial biotechnology. Before joining Formulatrix, he held positions as a research officer at the University of Punjab and as a lecturer at Lahore Garrison University.