About
Maintaining induced pluripotent stem cells (iPSCs) is a fundamental yet labor-intensive aspect of stem cell research and regenerative medicine. iPSC culture demands daily or near-daily monitoring to assess confluency, perform media exchanges, and ensure that cells remain undifferentiated and healthy, particularly during passaging. This routine is time-consuming, requires significant manual effort, and is susceptible to variability, which can lead to inconsistent cell quality and suboptimal maintenance if standardized best practices are not followed.
To address these challenges, Formulatrix’s Cellmatic provides advanced automation tools designed for iPSC maintenance. This system integrates automated imaging, scheduled media exchange and clump passaging, and reliable documentation into a unified workflow. Liquid handlers, including the FLO i8 and the Reagent Exchanger (RX), are responsible for executing media exchange and passaging tasks. This reduces manual workload, minimizes human error, and improves reproducibility, enabling researchers to maintain high-quality iPSC cultures more efficiently while conserving time and resources.