Virus-Like Particles (VLPs) are non-infectious self-assembling protein nanostructures, making them promising candidates for vaccines and targeted drug delivery.
However, the purification of VLPs presents significant challenges due to potential structural damage impacting their functionality. Conventional purification methods, such as ultracentrifugation, precipitation, column chromatography, and dead-end filtration, are limited by low volumes, high cost, poor scalability, and slow processing.
In this webinar, we will demonstrate the use of the µPULSE-TFF system to harvest extracellular VLPs as a walk-away, single-step, gentle, and fast approach, compared to dead-end centrifugal units. The µPULSE-TFF system also offers scalability, ease of use, and cost-effectiveness, thus facilitating efficient processing of larger VLP volumes and other macromolecules.
About the Speaker:
Muhammad Sajed is currently working at FORMULATRIX as an application scientist for the µPulse-TFF system and its applications in biological research. His areas of expertise include the production and purification of therapeutic enzymes, cell culturing, and industrial biotechnology. Before joining FORMULATRIX, he held positions as a research officer at the University of Punjab and as a lecturer at Lahore Garrison University.