Publications

@article{noKey,

title = {Design of Experiments useful statistical tool in assay development or vendor disconnect!},

url = {https://www.ddw-online.com/media/32/2273/winter-2009-design-of-experiments.pdf},

doi = {undefined},

year  = {2009},

date = {2009-01-01},

abstract = {The use of design of experiments (DOE) in assay development (AD) has the potential to speed up assay optimisation (ie reduce assay development bottlenecks) and to facilitate a more thorough evaluation of assay variables. Only one liquid handling vendor currently offers application specific software and support for investigating DOE in biological assays. Although standalone DOE software packages are available,  these were not written specifically for biological applications and they vary in their suitability for  AD.  DOE needs to be simpler to implement to make a major impact on  AD. A market opportunity exists for a turnkey solution that directly links statistical design with automated liquid handler programming and also feeds the assay readout directly into the statistical analysis,  to suggest and facilitate further iterative retesting.  Until new tools or more encompassing solutions emerge,  the full impact of DOE on  AD is unlikely to be realised.},

keywords = {FORMULATOR},

pubstate = {published},

tppubtype = {article}

}