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Automation of Single Cell Plating Utilizing the TEMPEST® Dispenser

Application Note

This study compares the dispensing and analysis of CHO-K1 cells to a 384-well plate using the automated FORMULATRIX TEMPEST® Liquid Dispenser versus an electric hand pipette.

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Using the TEMPEST® Liquid Dispenser to Improve an Automated High Throughput AlphaLISA® Assay

Application Note | Webinar

The success of this project was facilitated by a number of key TEMPEST features, namely an in-built capacity to recirculate the AlphaLISA beads, the ability to dispense multiple reagents from a single dispenser, and extremely low dead volumes.

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Miniaturization of a Hit Confirmation Run of 12,000 Concentration-Response Curves Using the TEMPEST Liquid Dispenser

Application Note

This application note highlights the use of the TEMPEST® Liquid Dispenser, a versatile microfluidic reagent dispenser designed to execute assay development and high-throughput screens in miniaturized assay volumes, driving down the cost of assay reagents by 60% while generating high-quality screening data.

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Miniaturization of Nextera XT Library Preparation for RNA-sequencing of Murine Neuronal Cell cDNA Samples using the MANTIS® Liquid Dispenser

Application Note

The combination of high-yield cDNA synthesis chemistry and high-precision low-volume reagent dispensing provides a workflow well-suited for large-scale RNA-Seq studies.

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Automation of Cell Viability Assays Utilizing Microfluidic Dispensing Technology

Application Note

One of the most widespread techniques to measure cellular viability is a luminescent CellTiter-Glo® (CTG) Assay, a homogeneous method based on quantitation of the ATP present, an indicator of metabolically active cells.

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Optimization of Automated AlphaLISA Assays for Biomarker Measurements in Large-Scale PK/PD Studies

Application Note

The AlphaLISA® technology (PerkinElmer, Inc., Waltham, MA) is a homogeneous no-wash alternative to conventional solid-phase ELISA assays that can be applied to biomarker detection in plasma and serum samples.

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