About
Exosomes are the nanosized lipid bi-layered extracellular vesicles involved in cell-to-cell communication. Their ability to fuse with cell membranes and evade phagocytosis makes them well-suited for targeted drug delivery, regenerative medicine, and diagnostics. However, harvesting and final formulation for downstream purification and applications are challenging tasks in the production workflow of exosomes.
The conventional methods such as ultracentrifugation and dead-end filtration are time inefficient and often limited by low yields and scalability. Additionally, these methods may damage the exosomes, compromising their structural integrity and consequently their bioactivity.
In this webinar, we will present case studies utilizing the µPulse TFF system in exosome production workflows. We will highlight how the µPulse workflow is a fast, gentle, and walk-away approach compared to dead-end filtration for exosome harvesting from culture media. Additionally, we will showcase the efficiency of the µPulse in the final formulation of exosomes purified from human plasma.
About the Speaker:
Muhammad Sajed is currently working at Formulatrix as an application scientist for the µPulse-TFF system and its applications in biological research. His areas of expertise include the production and purification of therapeutic enzymes, cell culturing, and industrial biotechnology. Before joining Formulatrix, he held positions as a research officer at the University of Punjab and as a lecturer at Lahore Garrison University.