Cell-based workflows play a vital role in the preclinical stages of drug discovery. These workflows involve dispensing cell suspensions or introducing other liquids into cell-containing plates. They necessitate the absence of cross-contamination, high throughput in liquid handling, gentle handling techniques, and the ability to maintain suspension homogeneity. Meeting these requirements poses significant challenges for both contact and conventional non-contact liquid handling approaches. Contact-based liquid handling, although well-established and gentle, carries the inherent risk of cross-contamination, limits throughput, and entails high operating costs.
On the other hand, non-contact dispensing addresses these issues. However, conventional non-contact dispensers have limitations of their own, such as being restricted in volume, subjecting samples to damaging forces, and having a poor ability to handle suspensions. The MANTIS and TEMPEST are non-contact dispensers that utilize proprietary microdiaphragm pump technology. In this webinar, we will discuss this technology and review several case studies that incorporate these instruments into diverse cell-based workflows, effectively meeting the demanding application requirements.
About the Speaker:
Dr. Usman Ashraf is an application scientist at FORMULATRIX, responsible for liquid handling systems and their applications in life science areas. He received his Ph.D. in Molecular Biology with research focused on targeting viral genomes using CRISPR/Cas technology. Before joining FORMULATRIX, he worked as an associate researcher and instructor at Lahore University of Management Sciences (LUMS), Pakistan.