Liquid Handling Technology

Intelligent Pipetting from FORMULATRIX®

Machine Vision

The worlds first deck-free automation platform employs cameras to simplify integration, removing the need to teach instrument and plate locations.

ROVER 2

Automated Liquid Transfer Optimization

The FLO I8 Liquid Handler aspirates and then dispenses 50% glycerol and water at different flow rates to maximize liquid transfer accuracy and precision without prior definition of liquid classes, source volumes, and labware geometry.

With time-consuming liquid class optimization, liquid handlers have been transferring liquids of varying viscosities and surface tensions for years.  Finally, FORMULATRIX® has developed a liquid handler that optimizes liquid transfers automatically.

Integrated pressure sensors in each pipetting channel independently monitor the aspiration and dispensing of samples and reagents, and react in real time to reproducibly pipette liquids of any viscosity and surface tension.  The algorithms embedded in the FLO I8 Liquid Handler uses this input to dynamically adjust pipetting parameters to achieve reproducible sample preparation.

Pipetting accuracy and precision are guaranteed without user adjustment of pipetting flow rate, equilibration time, or offsets for various liquid classes.

Dynamic Liquid Level Detection and Tracking

The FLO I8 Liquid Handler takes liquid level detection and tracking to the next level with sensors that enable dynamic liquid level tracking without prior definition of labware well profiles. 

Scientists can focus on their experiments instead of programming complex parameters. 

Protocols can be designed quickly and easily, making the FLO I8 a viable replacement for manual pipettes as the tool of choice for simple liquid handling tasks like a serial dilution of 1-8 samples. 

The FLO I8 Liquid Handler's eight channels independently detect and track liquid levels of eight samples dynamically without prior definition of labware geometries and source volumes.

The First Liquid Handler With The Sense of Touch

The FLO I8 Liquid Handler senses the bottom of the well prior to dispensing a sample and then senses the side of the well for a tip touch without prior definition of labware geometry.

Before dispensing into an empty plate, tip touch sensors detect the bottom or sides of the well in order to enable researchers to use any SBS footprint microtiter plate without programming the dimensions of the labware.

The pipette touch sensors also facilitate best-in-class error management and safety by detecting collisions with obstructions and halting motion before causing damage. Researchers can simply remove the obstruction and the FLO I8 will continue from where it left off. 

The FLO I8 touch sensor can detect a collision with only 30 grams of force and the position of the pipette tip is repeatable to within 50 microns.